The present study describes a simple, specific, sensitive, rapid and economical u.v. spectroscopy method for estimation amoxicillin trihydrate concentration in pH sensitive formulation. The absorption maxima or λmax of the drug was found to be nm. A linear response was observed in the range of µg/ml in. Spectrophotometric Estimation of Amoxicillin Trihydrate. Experimental. Instrument. All the spectral and absorbance measurements were made on an ELICO SL, UV-VIS spectrophotometer by using 1 cm match quartz cells. Materials. Amoxicillin trihydrate used in the present investigation is obtained from Tini.
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Apparatus. All spectral and absorbance measurements were performed on an Optima Spectrophotometer. UV - VIS (Japan) double-beam and using 1 cm quartz cells. Preparation of solutions. 1-Amoxicillin trihydrate (AMX) stock standard solution( µg mL-1) ( ×M) was prepared by dissolving g of pure. In original UV spectrophotometry, absorbances were measured at nm in the zero order UV spectra of the solution of amoxicillin in N NaOH in the range of - nm. In first derivative UV spectrophotometry, dA/dX values were measured at nm in the first derivative UV spectra of the solution of amoxicillin in.
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