Thank you, I am about to start taking Sertraline and although I don't drink a lot, I do like the occasional glass of wine. Report this · ❤ 0 . I have been reading about the effects of alcohol whilst taking sertraline and stupidly on Sunday I went to a lovely garden party and drank way too much. Today is tuesday Alcohol and sertraline | Sertraline. I wouldn't drink while on Zoloft.